P-ANILINESULFONIC ACID SODIUM SALT
sodium sulphanilate
CAS: 515-74-2
Molecular Formula: C6H8NNaO3S
P-ANILINESULFONIC ACID SODIUM SALT - Names and Identifiers
| Name | sodium sulphanilate |
| Synonyms | SODIUM SULFANILATE Sodium Sulfanilate sodium sulphanilate SODIUM ANILINESULFONATE 4-SULFOANILINE SODIUM SALT SULFANILIC ACID SODIUM SALT Sulfanilic Acid Sodium Salt SULPHANILIC ACID SODIUM SALT (4-aminophenyl)sulfonyloxysodium P-ANILINESULFONIC ACID SODIUM SALT 4-AMINOBENZENESULFONIC ACID SODIUM SALT 4-amino-benzenesulfonicacimonosodiumsalt 4-Amino-Benzenesulfonic Acid Monosodium Salt |
| CAS | 515-74-2 |
| EINECS | 208-208-5 |
| InChI | InChI=1/C6H7NO3S.Na/c7-5-1-3-6(4-2-5)11(8,9)10;/h1-4H,7H2,(H,8,9,10);/q;+1/p-1/rC6H6NNaO3S/c7-5-1-3-6(4-2-5)12(9,10)11-8/h1-4H,7H2 |
P-ANILINESULFONIC ACID SODIUM SALT - Physico-chemical Properties
| Molecular Formula | C6H8NNaO3S |
| Molar Mass | 197.18 |
| Appearance | Crystalline powder |
| Storage Condition | Inert atmosphere,Room Temperature |
| Physical and Chemical Properties | Flaky crystal with two molecules of crystal water. soluble in water. |
| Use | For the manufacture of dyes, spices, but also for the control of wheat rust |
P-ANILINESULFONIC ACID SODIUM SALT - Upstream Downstream Industry
| Raw Materials | Aniline Sodium carbonate Sulfanilic acid Sulfuric acid |
| Downstream Products | Reactive Dark Blue M-2ge |
P-ANILINESULFONIC ACID SODIUM SALT - Reference
| Reference Show more | 1. Zhao Yan, Hou Yingying, Tang Guosheng, etc. Inhibitory activity of different extracts of herba epimedii before and after processing on ACE, α-glucosidase and nitrite scavenging activity [J]. Journal of Pharmaceutical Analysis, 2015 (Issue 8):1329-1334. |
P-ANILINESULFONIC ACID SODIUM SALT - Nature
Open Data Verified Data
flash plate-like crystals with two molecules of crystal water. Soluble in water, its aqueous solution is neutral.
Last Update：2024-01-02 23:10:35
P-ANILINESULFONIC ACID SODIUM SALT - Preparation Method
Open Data Verified Data
aniline is sulfonated with concentrated sulfuric acid at 155~160 ℃ to prepare aniline sulfate, which is translocated into p-aminobenzene sulfonic acid at 180~215 ℃, and then neutralized with sodium carbonate to obtain p-aminobenzene sulfonic acid sodium, with activated carbon decolorization, Suction filtration, concentration, cooling crystallization, centrifugal dehydration, to get the finished product.
Last Update：2022-01-01 10:55:32
P-ANILINESULFONIC ACID SODIUM SALT - Use
Open Data Verified Data
acid dyes, direct dyes, reactive dyes and anti-dyeing agent H, soluble salt B, whitening agent BG and other additives can be prepared. It can also be used as a pesticide, and is mainly used to control wheat rust.
Last Update：2022-01-01 10:55:32
P-ANILINESULFONIC ACID SODIUM SALT - Safety
Open Data Verified Data
- The sulfonated product of aniline in this strain is far less toxic than aniline. See m-aminobenzenesulfonic acid.
- the use of iron barrels or bags, lined with plastic bags. 25kg or 50kg per bucket (bag). Store in a cool, dry and ventilated place to prevent moisture deterioration and avoid collision during handling.
Last Update：2022-01-01 10:55:33
P-ANILINESULFONIC ACID SODIUM SALT - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| background and overview | due to the relatively simple production process of p-aminobenzene sulfonic acid and sodium salt, China started production very early. The output of p-aminobenzenesulfonic acid was 1500 tons in 1990, 2000 tons in 1991 and 1100 tons in 1992. This production enterprise is dominated by state-owned manufacturers. With the rapid development of the domestic chemical industry and the rise of private enterprises, almost all the enterprises producing p-aminobenzenesulfonic acid and p-aminobenzenesulfonate are private enterprises. Many enterprises are flexible in production and produce p-aminobenzenesulfonic acid and sodium p-aminobenzenesulfonic acid according to actual market demand and inventory adjustment. At present, there are more than ten domestic production enterprises of sodium p-aminobenzenesulfonate, with a scale of more than 1,000 tons and a total production capacity of 4000 tons/year. From 2005 to 2010, the average annual growth rate of p-aminobenzenesulfonic acid was about 2. 50%. domestic p-aminobenzenesulfonic acid is mainly used for dyes, followed by pesticide sodium dirust, and is also used in water reducing agents, spices, pharmaceutical intermediates and other chemical industries. At present, the domestic production is large and demand, and some excellent products are exported in China, with less imports. At present, the shadow of the financial crisis has passed, and the domestic chemical industry has obviously recovered its vitality. It is expected that due to the impact of the international economic crisis in the next few years, the domestic production of p-aminobenzenesulfonic acid will grow at about 2%-3%, while downstream product dyes are also showing an obvious upward trend. |
| drug overview | general name: disodium English name: sodium p-aminobenzenesulfonate chemical name: sodium p-aminobenzene sulfonate Cas No: 515-74-2 molecular weight: 195.17 molecular formula: NaC6H4(NH2)SO3 structural formula: |
| Preparation method | is obtained by transposition and neutralization of aniline sulfonation. |
| production process flow chart | add 98% sulfuric acid into the oil bath sulfonation kettle, stir for 1 hour, add 99% aniline, raise the temperature of the kettle to 160 ℃, turn on the vacuum system to make the vacuum degree in the kettle 0.053MPa, then raise the temperature of the kettle to 200 ℃, keep the temperature for half an hour, raise the temperature to 260 ℃ again, and keep the temperature until the transposition is completed. At this time, cool down, close the vacuum system, keep it for 10 minutes, discharge the vacuum in the kettle, and gradually cool down to 80 ℃. Add water, stir and put into a storage tank. In the storage tank, the material is heated to 70~80 ℃, sodium carbonate is added to neutralize to pH = 7.0~7.5, transferred to the neutralization kettle that has been added to the previous batch of mother liquor, add water to adjust the relative density to 1.12, and heat to Boiling, add activated carbon, stir for half an hour, heat filtration, wash the filter cake with water, evaporate the filtrate to a relative density of 1.18, put it in the crystallization kettle, and cool to 30 ℃ within 8 hours, centrifugal filtration, the filtrate is used as the mother liquor for the next batch of neutralization, and the filter cake is sodium p-aminobenzene sulfonate. |
| use | a fungicide. It is mainly used to control rust of wheat and rust of other crops. To prevent and control wheat rust, spray with 250 times of the original medicine, and apply the medicine when the disease point and tablet occur, and the general green rises significantly. Spray once every 7-10 days for a total of 2-3 times. If 0.05kg of washing powder is added to every 50kg of liquid medicine, the spreading property can be increased and the prevention rate can be improved. To prevent and control broad bean and pea rust, spray with 300 times of the original medicine and apply the medicine once every 7-10 days. acid dyes, direct dyes, reactive dyes, anti-dyeing agent h, melting salt B, whitening agent BG and other additives can be prepared. In addition, it is also an ideal raw material intermediate for spices, food pigments, medicine, building materials and other industries. [specifications] plastic bags, 25kg per bag, plus woven bags. It has certain permeability and long residual period. It is mainly used to control wheat rust and other crop rust. To prevent and control wheat rust, spray with 250 times of the original medicine and spray it again every 7~10 days for 2~3 times. If 0.05kg of soap powder is added to 50kg of liquid medicine, the viscosity can be increased and the control effect can be improved. dye intermediates are used for acid orange ii, acid tender yellow 2G, acid medium yellow brown 4G, acid medium deep yellow GG, direct yellow GR, active yellow K-RN, brilliant red K-10B, brilliant red K-2G, jujube red K-DG, purple K-3R, etc. It is also used to manufacture printing and dyeing auxiliaries, such as dissolved salt B, fluorescent whitening agent BG, anti-dyeing salt H, etc. And a large number of pesticides to control wheat rust. It is used to make dyes and spices, and also to prevent and control wheat rust |
| first aid method | skin contact: remove contaminated clothes and rinse with flowing water. Eye contact: Lift the eyelids, rinse with flowing water or normal saline, and seek medical treatment. Inhalation: leave the scene to fresh air. If you have difficulty breathing, give oxygen and seek medical attention. Ingestion: Drink enough warm water, induce vomiting, and seek medical treatment. |
| protective measures | p-aminobenzenesulfonic acid atlas engineering control: closed operation, local exhaust. respiratory system protection: when the dust concentration in the air exceeds the standard, you must wear a self-priming filter dust mask. An air respirator should be worn during emergency rescue or evacuation. Eye protection: Wear chemical safety protective glasses. Body protection: wear anti-toxin penetration work clothes. Hand protection: Wear rubber gloves. Other protection: After work, shower and change clothes. Pay attention to personal cleanliness. Regular physical examination. |
| storage and transportation items | the packaging should be complete and the loading should be safe. During transportation, ensure that the container does not leak, collapse, fall or damage. It is strictly prohibited to mix with oxidants, acids, alkalis, edible chemicals, etc. During transportation, it should be protected from sun exposure, rain and high temperature. The vehicle shall be thoroughly cleaned after transportation. Store in a cool, ventilated warehouse. Stay away from fire and heat sources. It should be stored separately from oxidants, acids and alkalis, and should not be mixed. The storage area shall be equipped with suitable materials to contain leaks. |
| leakage treatment method | leakage treatment method: isolate the leakage pollution area and restrict access. It is recommended that emergency personnel wear dust masks (full masks) and anti-virus clothing. Avoid dust, sweep it carefully, place it in a bag and transfer it to a safe place. If there is a large amount of leakage, cover with plastic cloth and canvas. Collect and recycle or transport to waste disposal sites for disposal. Abandonment method: Disposal according to the requirements of relevant national and local regulations. Or contact the manufacturer or manufacturer to determine the disposal method. |
| operation and storage | precautions for operation: airtight operation, local exhaust. Operators must undergo special training and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter dust masks, chemical safety protection glasses, anti-toxin penetration overalls and rubber gloves. Avoid producing dust. Avoid contact with oxidants, acids, and alkalis. When handling, it should be lightly loaded and unloaded to prevent damage to the packaging and containers. Equipped with leakage emergency treatment equipment. Empty containers may remain harmful substances. |
| storage precautions | store in a cool and ventilated warehouse. Stay away from fire and heat sources. It should be stored separately from oxidants, acids and alkalis, and should not be mixed. The storage area shall be equipped with suitable materials to contain leaks. |
| toxicity | low toxicity to humans and animals, acute oral LD503000mg/kg in mice, no irritation to skin. Carp LC507.57 mg/L (48h). |
| production method | aniline sulfonation and translocation: the technological process is as follows: 1. translocation (sulfonation reaction) 450kg of 98% sulfuric acid is added into the drum reactor. 400kg of aniline (99%) was added within 1h after the drum was rotated. Raise the furnace temperature to 160 ℃, and turn on the jet pump to make the vacuum degree of the system above 53.3kPa. The furnace temperature is raised to 200 ℃ for 0.5h. Continue to raise the temperature to 260 ℃ and keep the temperature until the transposition is completed. The end point is the sound of black powder and iron ball in the mirror, cool down, turn off the jet pump, and rotate for 10min. Exhaust air, cool to 80 ℃, add 2500L of water, rotate and mix, and put into the trough. 2. Neutralize in the trough, the material is heated to 70-80 ℃, and sodium carbonate (about 230kg) is added to neutralize to pH = 7-7.5. Move it into a neutralization pot with 600L mother liquor and adjust the relative density to about 1.12. Heat to boiling, add 4kg of activated carbon and stir for 0.5h. Hot filtration, filter residue washed with hot water; The filtrate is concentrated to a relative density of about 1.18. Put in the crystallization barrel and cool to 30°C for 8h. Centrifugal filtration, filtrate as the next batch of mother liquor; The filter cake is sodium sulfamate (about 850kg). The total yield is 86.5%. Product specification: HG2---372--80. The appearance is pink or light rose crystals, and the content is ≥ 97.0%. Raw material consumption quota: aniline (99%)460 kg/t, soda ash (98%)264 kg/t, sulfuric acid (98%)492 kg/t. sulphonation of aniline to produce p-aminobenzenesulfonic acid, p-aminobenzenesulfonic acid and sodium carbonate or sodium hydroxide, and after decolorization, concentration, crystallization, drying and other post-treatment to produce dirust sodium, industrial products with 2 sub crystal water. |
Last Update：2024-04-09 02:00:09
Supplier List
Featured ProductsSpot supply
Product Name: sodium sulphanilate Request for quotationCAS: 515-74-2
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Product Name: sodium sulphanilate Request for quotation
CAS: 515-74-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 515-74-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: sodium sulphanilate Request for quotationCAS: 515-74-2
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Multiple SpecificationsSpot supply
Product Name: sodium sulphanilate Request for quotationCAS: 515-74-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Sodium 4-aminobenzenesulfonate Visit Supplier Webpage Request for quotationCAS: 515-74-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Multiple Specifications
Product Name: 4-Amino-benzenesulfonic acid monosodium salt Request for quotationCAS: 515-74-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: 4-Amino-benzenesulfonic acid monosodium salt Visit Supplier Webpage Request for quotationCAS: 515-74-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: 4-Amino-benzenesulfonic acid monosodium salt Visit Supplier Webpage Request for quotationCAS: 515-74-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: sodium sulfanilate Request for quotation
CAS: 515-74-2
Tel:
Email: 285188773@qq.com
Mobile: 13673210091
QQ: 285188773
Send QQ message
CAS: 515-74-2
Tel:
Email: 285188773@qq.com
Mobile: 13673210091
QQ: 285188773
Product Name: sulfanilic acid sodium salt Request for quotation
CAS: 515-74-2
Tel: 15533675005
Email: 27475469@qq.com
Mobile: 15533675005
QQ: 27475469
Send QQ message
CAS: 515-74-2
Tel: 15533675005
Email: 27475469@qq.com
Mobile: 15533675005
QQ: 27475469
Featured ProductsSpot supply
Product Name: sodium sulphanilate Request for quotationCAS: 515-74-2
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Product Name: sodium sulphanilate Request for quotation
CAS: 515-74-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 515-74-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: sodium sulphanilate Request for quotationCAS: 515-74-2
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Multiple SpecificationsSpot supply
Product Name: sodium sulphanilate Request for quotationCAS: 515-74-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Sodium 4-aminobenzenesulfonate Visit Supplier Webpage Request for quotationCAS: 515-74-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Multiple Specifications
Product Name: 4-Amino-benzenesulfonic acid monosodium salt Request for quotationCAS: 515-74-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: 4-Amino-benzenesulfonic acid monosodium salt Visit Supplier Webpage Request for quotationCAS: 515-74-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: 4-Amino-benzenesulfonic acid monosodium salt Visit Supplier Webpage Request for quotationCAS: 515-74-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: sodium sulfanilate Request for quotation
CAS: 515-74-2
Tel:
Email: 285188773@qq.com
Mobile: 13673210091
QQ: 285188773Send QQ message
CAS: 515-74-2
Tel:
Email: 285188773@qq.com
Mobile: 13673210091
QQ: 285188773
Product Name: sulfanilic acid sodium salt Request for quotation
CAS: 515-74-2
Tel: 15533675005
Email: 27475469@qq.com
Mobile: 15533675005
QQ: 27475469Send QQ message
CAS: 515-74-2
Tel: 15533675005
Email: 27475469@qq.com
Mobile: 15533675005
QQ: 27475469
View History
P-ANILINESULFONIC ACID SODIUM SALT
6-(3-氯丙氧基)-2-(4-(3-氯丙氧基)苯基)苯并恶唑
1-ETHYL-2,3-DIMETHYLIMIDAZOLIUM BROMIDE
1-(4-Chlorophenyl)-2-morpholinoethanone hydrochloride
6-(3-氯丙氧基)-2-(4-(3-氯丙氧基)苯基)苯并恶唑
1-ETHYL-2,3-DIMETHYLIMIDAZOLIUM BROMIDE
1-(4-Chlorophenyl)-2-morpholinoethanone hydrochloride
Raw Materials for P-ANILINESULFONIC ACID SODIUM SALT
Downstream Products for P-ANILINESULFONIC ACID SODIUM SALT